Multidrugresistance相关论文
目的:探讨上海市浦东新区腹泻患者小肠结肠炎耶尔森菌的流行特征状况。方法:回顾性分析2013年1月至2019年12月，上海市浦东新区疾病......
Traditional chemotherapy exhibits a certain therapeutic effect toward malignant cancer,but easily induce tumor multidrug......
目的:分析乐山市人民医院鲍曼不动杆菌(acinetobacter baumannii,ABA)临床感染的特点、耐药性,为医院感染的防控和抗菌药物的合理......
Combined nanosuspensions from two natural active ingredients for cancer therapy with reduced side ef
Tumor drug resistance and systemic side effects of chemotherapeutic drugs are the main reasons for the failure of cancer......
Codelivery of drugs by drug carriers is a promising strategy against several diseases such as infections and cancer.Howe......
With the emergence of multidrug resistance (MDR) in many pathogens,bacterial infections are becoming a growing threat to......
Polyoxypregnanes as safe,potent,and specific ABCB1-inhibitory pro-drugs to overcome multidrug resist
Multidrug resistance(MDR)mediated by ATP binding cassette subfamily B member 1(ABCB1)is significantly hindering effectiv......
Silencing of ER-resident oxidoreductase PDIA3 inhibits malignant biological behaviors of multidrug-r
Glycosylation is a common posttranslational modification of proteins,which plays a role in the malignant transformation,......
Curcumin Reverses 5-Fluorouracil Resistance by Promoting Human Colon Cancer HCT-8/5-FU Cell Apoptosi
Objective:To investigate the potential mechanisms that curcumin reverses 5-fluorouracil (5-FU) multidrug resistance (MDR......
Multidrug resistance (MDR) is a major cause of cancer chemotherapy failure,and it is important to develop suitable rever......
Multidrug resistance (MDR) is one of the major obstacles in cancer chemotherapy.Our previous study has shown that icarii......
Eight new annonaceous acetogenins,squamotin A-D (1-4),annosquatin Ⅳ-Ⅴ (5 and 6),muricin O (7) and squamosten B (8),tog......
Multidrug resistance (MDR) in human cancer is one of greatest challenges in cancer therapy. Natural products, especially......
Chemoresistance is a major barrier against effective treatment outcomes in cancer.MDR cancer cells can survive through c......
A simple Paclitaxel (PTX) prodrug based on TPGS and disulfide bond (TPGS-S-S-PTX) was synthesized by a two step esterifi......
Most of present nano-drug delivery systems are developed to target cancer cells, rarely nuclei.However, the nuclear-targ......
Co-Delivery of a π-π Stacked Dual Anticancer Drug Combination with Nanocarriers for Overcoming Multi
Despite progress, combination therapy of various functional drugs to enhance the efficiency against multidrug resistance......
Single-Step Assembly of DOX/ICG Loaded Lipid-Polymer Nanoparticles for Fluorescence Trace and Combin
Combination of chemotherapy and photothermal therapy has emerged as a promising strategy for cancer therapy.To assure th......
pH-sensitive docetaxel-loaded TPGS-poly(β-amino ester) copolymer nanoparticles for overcoming multid
Multidrug resistance (MDR) is one of the major obstacles to successful chemotherapy.Overexpression of drug efflux transp......
Polymer inhibitors of ABC transporter overcoming multidrug resistance:synthesis,characterization and
One of the most significant problems of chemotherapy is that even originally very sensitive tumors become often resistan......
Characterization of A Novel Hybrid IncC Plasmid Mediating Multidrug Resistance Recovered from Proteu
1 Introduction Proteus mirabilis is an important opportunistic pathogen in large-scale chicken farms,threatening food sa......
Polymer inhibitors of ABC transporter overcoming multidrug resistance: synthesis,characterization an
One of the most significant problems of chemotherapy is that even originally very sensitive tumors become often resistan......
Hybrid lipid-mesoporous silica for stimuli-responsive drug release and overcoming multidrug resistan
Multidrug resistance (MDR) is always an impediment to successful chemotherapy and considerable efforts have been devoted......
Gold Nanorod-Cored Micelles as a Remotely-Controllable Near IR-Triggered Drug Release System for Eff
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Doxorubicin (DOX) is a widely used chemotherapeutic drug for the treatment of several types of cancers.However,its side ......
目的 The expression of ATP-binding cassette subfamily G member 2(ABCG2)in manycancers was correlated with development of......
Evodiamine,has therapeutic potential in drug resistance by targeting HIF-1α in hypoxic microenvironm
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Reduced 5-Hydroxymethylcytosine is an Epigenetic Marker for Chemotherapy Resistance and Immune Evasi
Objective Multidrug resistance is a major challenge for the treatment of advanced hepatocellular carcinoma(HCC).Although......
Transcriptome sequencing Reveals the Potential Roles of driven genes in Chemotherapy-induced multidr
目的： Lung cancer is the leading cause of cancer-related deaths in China, currently, lun adenocarcinoma has become the ma......
Innovative co-delivery system of siRNA and Doxorubicin aimed to reversal multidrug resistance via su
P-glycoprotein(P-gp)plays an importantrole in multi-drug resistance(MDR),proved to be one of the major obstacles in canc......
Multidrug resistance(MDR)is the primary impediment to thesuccess ofchemotherapy and thus effective treatments need the a......
Construction of Tanshinone I-Based Diverse Compound Library by DOS for Overcoming Tumor Multidrug Re
Most of tumor treatment failure is ascribed to multidrug resistance,which involves in almost all types of tumors and wit......
Background Hepatocellular carcinoma (HCC) is the fifth most common cancer worldwide and ranks second among all the prima......
Paclitaxel and Cryptotanshinone Loaded Temporal-controlled Nanoparticles for Combinatorial Cancer Th
Combination therapy has emerged as a promising strategy for treating multidrug resistant (MDR) cancer.In the previous st......
Reversion of multidrug resistance by coadministration of doxorubicin and bromotetrandrine in polymer
Female breast cancer is one of the most common cancers among middle aged and older women.According to NCI statistics, th......
Gambogic Acid as a Non-competitive Inhibitor of ABCB1 Reverses the Multidrug Resistance of Human Epi
Gambogic acid (GA) is known for its anticancer activity in a phase Ⅱ clinical trial.However, the detailed molecular mec......
In vitro activity of combinations of rifampin with other antibiotics against multidrug-resistant Aci
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Malignant tumors are serious diseases that seriously threaten human health.The treatment is mainly based on surgical tre......
Egr-1 enhances drug resistance of breast cancer by modulating MDR1 expression in a GGPPS-independent
The multidrug resistance 1 (MDR1) gene product P-glycoprotein is an ATP-dependent efflux pump associated with chemothera......
Amphiphilic Copolymeric Micelles for Doxorubicin and Curcumin Co-delivery to Reverse Multidrug Resis
Development of multidrug resistance against chemotherapeutic drugs is one of the major obstacles to successful cancer th......
Quercetin and Doxorubicin Co-encapsulated Biotin Receptor-targeting Nanoparticles for Minimizing Dru
The combination of a chemotherapeutic drug with a chemosensitizer has emerged as a promising strategy for cancers showin......
The study of N-succinyl chitosan-poly-L-lysine-palmitic acid triblock polymer micelle for co-deliver
Background: It is the hot issue that targeting therapy and reversing multidrug resistance are used to improve therapeuti......
Nowadays, lots of investigators draw attention to multidrug resistance(MDR) in cancer.The MDR is mostly due to the overe......
Coniferyl ferulate, a strong Inhibitor of Glutathione-S-transferase Isolated from Radix Angelicae si
Aim: Glutathione-S-transferase (GST) is key enzyme in multidrug resistance (MDR) of tumor.Inhibition of the expression o......
To search for better P-glycoprotein-(Pgp-)mediated multidrug resistance(MDR)modulators,we designed and synthesized a ser......
